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Kétamine basse dose à visée antalgique

TopMédecine

La kétamine aux urgence est de plus en plus utilisée depuis plus de 15 ans dans de multiples indications. L’usage en antalgie simple à basse posologie est de plus en plus documenté , et particulièrement efficace sur les douleurs intenses résistantes.

Pour mieux connaître les perfusions de certains médicaments associés à cette capsule, veuillez consulter l’application EZResus

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Ce cours a été conçu par Justin Outrey et Pascal Mattei le mercredi 9 mars 2022.



Bibliographie

pubmed
Low-dose Ketamine For Acute Pain Control in the Emergency Department: A Systematic Review and Meta-analysis.
Balzer N,McLeod SL,Walsh C,Grewal K, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2021 Apr 28(4) 444-454
pubmed
A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED.
Motov S,Mai M,Pushkar I,Likourezos A,Drapkin J,Yasavolian M,Brady J,Homel P,Fromm C, The American journal of emergency medicine 2017 Aug 35(8) 1095-1100
pubmed
Slow Infusion of Low-dose Ketamine Reduces Bothersome Side Effects Compared to Intravenous Push: A Double-blind, Double-dummy, Randomized Controlled Trial.
Clattenburg EJ,Hailozian C,Haro D,Yoo T,Flores S,Louie D,Herring AA, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2018 Sep 25(9) 1048-1052
pubmed
Principles of pharmacotherapy: III. Drug allergy.
Pallasch TJ, Anesthesia progress 1988 Sep-Oct 35(5) 178-89
pubmed
Administration of Nebulized Ketamine for Managing Acute Pain in the Emergency Department: A Case Series.
Drapkin J,Masoudi A,Butt M,Hossain R,Likourezos A,Motov S, Clinical practice and cases in emergency medicine 2020 Feb 4(1) 16-20
pubmed
Intravenous Subdissociative-Dose Ketamine Versus Morphine for Analgesia in the Emergency Department: A Randomized Controlled Trial.
Motov S,Rockoff B,Cohen V,Pushkar I,Likourezos A,McKay C,Soleyman-Zomalan E,Homel P,Terentiev V,Fromm C, Annals of emergency medicine 2015 Sep 66(3) 222-229.e1
pubmed
The Use of Ketamine for Acute Treatment of Pain: A Randomized, Double-Blind, Placebo-Controlled Trial.
Sin B,Tatunchak T,Paryavi M,Olivo M,Mian U,Ruiz J,Shah B,de Souza S, The Journal of emergency medicine 2017 May 52(5) 601-608
pubmed
Substantial Elevation of Liver Enzymes During Ketamine Infusion: A Case Report.
Zhu X,Kohan LR,Goldstein RB, A&A practice 2020 Jun 14(8) e01239
pubmed
A randomized, noninferiority, controlled trial of two doses of intravenous subdissociative ketamine for analgesia in the emergency department.
Lovett S,Reed T,Riggs R,Lew G,Koch E,Durazo-Arvizu RA,Rech MA, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2021 Jun 28(6) 647-654
pubmed
Ketamine for the treatment of acute pain.
Silverstein WK,Juurlink DN,Zipursky JS, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2021 Nov 1 193(43) E1663

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